Use of two-component signal transduction systems in the construction of synthetic genetic networks
نویسندگان
چکیده
منابع مشابه
Two-component systems in plant signal transduction.
In plants, two-component systems play important roles in signal transduction in response to environmental stimuli and growth regulators. Genetic and biochemical analyses indicate that sensory hybrid-type histidine kinases, ETR1 and its homologs, function as ethylene receptors and negative regulators in ethylene signaling. Two other hybrid-type histidine kinases, CKI1 and ATHK1, are implicated i...
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Most prokaryotic signal-transduction systems and a few eukaryotic pathways use phosphotransfer schemes involving two conserved components, a histidine protein kinase and a response regulator protein. The histidine protein kinase, which is regulated by environmental stimuli, autophosphorylates at a histidine residue, creating a high-energy phosphoryl group that is subsequently transferred to an ...
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چکیده ندارد.
15 صفحه اولRewiring the Specificity of Two-Component Signal Transduction Systems
Two-component signal transduction systems are the predominant means by which bacteria sense and respond to environmental stimuli. Bacteria often employ tens or hundreds of these paralogous signaling systems, comprised of histidine kinases (HKs) and their cognate response regulators (RRs). Faithful transmission of information through these signaling pathways and avoidance of detrimental crosstal...
متن کاملNovel domains of the prokaryotic two-component signal transduction systems.
The archetypal two-component signal transduction systems include a sensor histidine kinase and a response regulator, which consists of a receiver CheY-like domain and a DNA-binding domain. Sequence analysis of the sensor kinases and response regulators encoded in complete bacterial and archaeal genomes revealed complex domain architectures for many of them and allowed the identification of seve...
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ژورنال
عنوان ژورنال: Current Opinion in Microbiology
سال: 2010
ISSN: 1369-5274
DOI: 10.1016/j.mib.2010.01.003